Requirements: English
Company: Iginnovate
Region: palinges , Vaud
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Posting Start Date: 5/7/25
Job Description:
About Us:
We are an innovative biotechnology company advancing next-generation bispecific antibody therapeutics using our proprietary BEAT platform. Join a team committed to transforming immuno-oncology treatments.
RA/Investigator In Vivo Pharmacology
Department: Immuno-Oncology II
Your Mission:
- Design, execute and analyze in vivo studies to characterize antibody-based therapeutics.
- Execute hands-on, in vivo work at all stages of animal experimentation, including in-life and ex vivo analysis.
- Isolate PBMCs and maintain primary human cells (e.g., T cells, NK cells, Monocytes) and cell lines in culture.
- Perform immune cell-based functional assays using primary human cells.
- Conduct phenotype analyses, activation or cytotoxicity assay using multicolor flow cytometry and multiplex cytokine profiling (i.e. ELISA, MSD, Luminex).
- Analyze data using Excel, GraphPad, FlowJo etc.
- Present findings in team meetings.
- Ensure compliance with HSE and BSL-2 biosafety standards.
- Document experiments
- Support laboratory operations and equipment maintenance.
Your Profile:
- Technical degree (RA position) or Bachelor/Master degree (Investigator position) with experience in immunology or oncology models in vivo.
- Strong experience with handling mice is mandatory.
- Active LTK1 certification is mandatory
- LTK2 is a plus.
- Experience in cell culture (human and murine cells) and flow cytometry is mandatory.
- Proficient in data analysis using standard software.
- Comfortable working in an English-speaking environment; fluency in French is a plus.
- Strong organizational and multitasking skills.
- Effective team player with excellent interpersonal communication skills.
- Experience with ELISA is a plus
- Experience with CDX models is highly desirable.
- Experience with humanized immune system models (CD34 or PBMC) is highly desirable.
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