Requirements: English
Company: Generare
Region: Paris , le-de-France
About Generare Generare is a young and dynamicbiotechnology company based in the heart of Paris, with a missionto discover and develop natural microbial products at scale fortherapeutic applications. Natural products have been a cornerstoneof medicine, yet traditional methods of discovery have plateaued.At Generare, we leverage a unique technology platform to uncoverhidden potential in the DNA of microbes, addressing urgentchallenges like antibiotic resistance while pushing the boundariesof science. Having successfully closed a seed round in mid-2024, weare now scaling up towards industrialization. Our ambitious roadmapincludes operating our first in-house production facility by early2027. This marks a pivotal step in scaling our platform to producebioactive compounds at unprecedented throughput and precision. Witha cutting-edge platform capable of discovering hundreds of newmolecules annually, we are scaling up to reach thousandsand weneed your expertise to make it happen. Introduction to GeneraresDiscovery Workflow Our discovery process focuses on uncoveringnovel bioactive compounds from microbial strains isolated from soilsamples collected across diverse environments. Usinghigh-throughput sequencing and advanced bioinformatics,biosynthetic gene clusters (BGCs) are prioritized and localized fortheir potential to encode drug-like molecules. These BGCs are thenexpressed in optimized microbial hosts, enabling the isolation ofnew-to-science natural products. The final step involvescharacterization and validation of these compounds using massspectrometry and other state-of-the-art analytical techniques. YourRole: Head of Industrial Operations As Head of IndustrialOperations, you will play a pivotal role in driving the industrialscalability of Generares discovery platform. You will oversee theoptimization of current production workflows, develop long-termproduction plans, and design scalable solutions to prepare formulti-site operations. Your dual focus on daily operations andstrategic planning will ensure that Generare meets its ambitiousgrowth targets. Your Key Responsibilities 1. Operational Excellence- Identify bottlenecks in the current production pipeline andimplement innovative solutions to address them - Develop, track,and optimize key performance metrics for high-throughput productionworkflows - Streamline and scale operational processes to improveefficiency and reproducibility 2. Annual and Long-Term ProductionPlanning - Lead the planning of production activities over annualcycles to align with company objectives - Forecast resource needs,set production targets, and ensure delivery milestones are met -Collaborate closely with R&D and leadership teams tosynchronize discovery efforts and production capacity 3. IndustrialScale-Up and Factory Design - Define the technical and operationalrequirements for Generares first in-house production facility, setto launch in 2027 - Drive the design and planning of a multi-siteproduction model for microbial natural compounds 4. Team Leadershipand Management - Oversee and inspire a multidisciplinary teamspanning microbiology, molecular biology, chemistry, andbioinformatics - Foster a culture of collaboration, innovation, andownership across the production pipeline Ideal Candidate Profile Weare looking for a driven, solutions-oriented leader (4+ yearsexperience) with the vision and skills to elevate Generaresindustrial operations to a global standard. Education: Degree inprocess engineering or a related field. Experience: Provenexpertise in scaling up industrial processes, ideally gained in thefood, cosmetics, or biotech sectors. Skills: - Mastery of processoptimization techniques and multi-site production management -Ability to identify and resolve complex production challenges -Strong skills in resource planning and capacity forecastingPersonal Qualities: Demonstrated leadership, a collaborativespirit, and a strong drive for operational excellence andinnovation. Why Join Us? - Be part of a groundbreaking mission torevolutionize natural product discovery and production. - Shape andlead the industrialization of a unique biotech platform. -Collaborate with passionate scientists and innovators in a dynamicand supportive environment. - Drive the transition from discoveryto scalable production with global impact. Interested? Send yourCV and a cover letter to anne-camille@generare.bio