Requirements: English
Company: Verley
Region: rhone-alpes, fr , Auverge-Rhne-Alpes
About us
Verley is a biotechnology company based in Lyon, focused on developing dairy proteins through precision fermentation. Our aim is to offer sustainable, high-quality alternatives to traditional animal-based ingredients, contributing to the evolution of food production methods. We bring together a team of scientists and engineers with complementary expertise, working to turn promising technologies into concrete applications for the food industry.
Position overview
As Senior DSP Engineer, you will be at the heart of Verleys scale-up strategy, ensuring a robust and efficient transition from lab-scale development to external manufacturing. Reporting to the Head of Industrialization, you will lead the design, optimization, and industrial translation of DSP (Downstream Processing) processes, acting as the technical bridge between RD and our contract manufacturing partners.
This role involves hands-on work, as well as frequent interactions with external partners to support scale-up and production with travel required to our CMOs in France, Mexico, Italy, and beyond.
Key Responsibilities
Process Development Scale-up
- Optimize and validate downstream processes (e.g. separation, filtration, chromatography, drying) developed at lab and pilot scale.
- Ensure process robustness and reproducibility as part of industrial transfer.
- Define process parameters and critical control points in preparation for industrial implementation.
Interface with CMOs (Production Scale)
- Act as the technical point of contact for DSP during the transfer and monitoring of production at CMOs.
- Support on-site DSP-related activities (e.g., scale-up trials, troubleshooting, batch reviews).
- Ensure alignment between lab-scale data and industrial performance, and propose improvements when needed.
- Contribute to the review and validation of production documentation (batch records, protocols, etc.).
Cross-functional Collaboration Documentation
- Collaborate with upstream, analytics, and QA teams to ensure coherent and scalable bioprocesses.
- Contribute to the drafting of tech transfer documentation, process descriptions, and risk assessments.
- Support continuous improvement initiatives based on production feedback and analytical results.
Key Competencies
- DSP Expertise: Strong practical knowledge of protein purification and DSP unit operations.
- Scale-up Mindset: Ability to translate lab-scale success into industrially viable, cost-effective solutions.
- Hands-on Analytical: Skilled in data analysis, troubleshooting, and root-cause investigation.
- Communication: Capable of articulating technical needs clearly to both internal and external stakeholders.
- Adaptability: Comfortable navigating a fast-paced environment and managing shifting priorities.
Who you are
- You have 5+ years of experience in DSP or industrial biotech, with a strong focus on process development and scale-up.
- You hold a degree in Biochemical Engineering, Biotechnology, Process Engineering, or equivalent.
- You have experience working with external manufacturing partners, ideally in a GMP or food-grade environment.
- Youre autonomous, structured, and proactive, with a taste for fieldwork and technical problem-solving.
- You are fluent in English; proficiency in French is a plus.
- You are open to regular travel (France and internationally) to support external production runs.